SOX2 Is a Marker for Stem-like Tumor Cells in Bladder Cancer

Summary: It has been reported that functionally distinct cancer stem cells (CSCs) exist in human bladder cancer (BCa). Here, we found that Sox2, a transcription factor that is well characterized as a marker for stem cells, is upregulated in both mouse and human BCa. Sox2 expression is absent in norm...

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Bibliographic Details
Main Authors: Fengyu Zhu, Weiqing Qian, Haojie Zhang, Yu Liang, Mingqing Wu, Yingyin Zhang, Xiuhong Zhang, Qian Gao, Yang Li
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117303144