Hormonal induction and roles of Disabled-2 in lactation and involution.

Disabled-2 (Dab2) is a widely expressed endocytic adaptor that was first isolated as a 96 KDa phospho-protein, p96, involved in MAPK signal transduction. Dab2 expression is lost in several cancer types including breast cancer, and Dab2 is thought to have a tumor suppressor function. In mammary epith...

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Bibliographic Details
Main Authors: Wensi Tao, Robert Moore, Elizabeth R Smith, Xiang-Xi Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4216001?pdf=render