UP Finder: A COBRA toolbox extension for identifying gene overexpression strategies for targeted overproduction

Overexpression of key genes is a basic strategy for overproducing target products via metabolic engineering. Traditionally, identifying those key genes/pathways largely relies on the knowledge of biochemistry and bioinformatics. In this study, a modeling tool named UP Finder was developed to facilit...

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Bibliographic Details
Main Authors: Xi Wang, Liang Yu, Shulin Chen
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Metabolic Engineering Communications
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214030117300202