Entamoeba histolytica-secreted cysteine proteases induce IL-8 production in human mast cells via a PAR2-independent mechanism

Entamoeba histolytica-secreted cysteine proteases induce IL-8 production in human mast cells via a PAR2-independent mechanism

Entamoeba histolytica is an extracellular tissue parasite causing colitis and occasional liver abscess in humans. E. histolytica-derived secretory products (SPs) contain large amounts of cysteine proteases (CPs), one of the important amoebic virulence factors. Although tissue-residing mast cells pla...

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Bibliographic Details
Main Authors: Lee Young Ah, Nam Young Hee, Min Arim, Kim Kyeong Ah, Nozaki Tomoyoshi, Saito-Nakano Yumiko, Mirelman David, Shin Myeong Heon
Format: Article
Language:English
Published: EDP Sciences 2014-01-01
Series:Parasite
Subjects:
Entamoeba histolytica
Cysteine protease
Mast cell
IL-8
Protease-activated receptor 2 (PAR2)
Online Access:http://dx.doi.org/10.1051/parasite/2014001

Internet

http://dx.doi.org/10.1051/parasite/2014001

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