Restoration of the striatal circuitry: from developmental aspects towards clinical applications

In the basal ganglia, the striatum is a highly complex structure coordinating motor and cognitive functions and it is severely affected in Huntington’s disease (HD) patients. Transplantation of fetal ganglionic eminence derived precursor cells aims to restore neural circuitry in the degenerated stri...

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Bibliographic Details
Main Authors: Marie-Christin ePauly, Tobias ePiroth, Máté eDöbrössy, Guido eNikkhah
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2012.00016/full