Subcellular Targeting Domains of Sphingomyelin Synthase 1 and 2

<p>Abstract</p> <p>Sphingomyelin synthase (SMS) sits at the crossroads of sphingomyelin (SM), ceramide, diacylglycerol (DAG) metabolism. It utilizes ceramide and phosphatidylcholine as substrates to produce SM and DAG, thereby regulating lipid messengers which play a role in cell s...

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Bibliographic Details
Main Authors: Yeang Calvin, Ding Tingbo, Chirico William J, Jiang Xian-Cheng
Format: Article
Language:English
Published: BMC 2011-12-01
Series:Nutrition & Metabolism
Online Access:http://www.nutritionandmetabolism.com/content/8/1/89