Overexpression of SGLT2 in the kidney of a P. gingivalis LPS-induced diabetic nephropathy mouse model

Abstract Background The overexpression of sodium-glucose cotransporter 2 (SGLT2) in diabetic kidneys has been reported. It has also been established that the diabetic glomerular endothelium expresses the toll-like receptors TLR2 and TLR4. The present study aims to examine the renal SGLT2 induction b...

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Bibliographic Details
Main Authors: Koichiro Kajiwara, Yoshihiko Sawa
Format: Article
Language:English
Published: BMC 2021-08-01
Series:BMC Nephrology
Subjects:
LPS
Online Access:https://doi.org/10.1186/s12882-021-02506-8