Replication competent HIV-1 viruses that express intragenomic microRNA reveal discrete RNA-interference mechanisms that affect viral replication

<p>Abstract</p> <p>Background</p> <p>It remains unclear whether retroviruses can encode and express an intragenomic microRNA (miRNA). Some have suggested that processing by the Drosha and Dicer enzymes might preclude the viability of a replicating retroviral RNA genome...

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Bibliographic Details
Main Authors: Klase Zachary, Houzet Laurent, Jeang Kuan-Teh
Format: Article
Language:English
Published: BMC 2011-11-01
Series:Cell & Bioscience
Subjects:
Online Access:http://www.cellandbioscience.com/content/1/1/38