Pharmacodynamic and Metabolomics Studies on the Effect of Kouyanqing Granule in the Treatment of Phenol-Induced Oral Ulcer Worsened by Sleep Deprivation

Pharmacodynamic and Metabolomics Studies on the Effect of Kouyanqing Granule in the Treatment of Phenol-Induced Oral Ulcer Worsened by Sleep Deprivation

Oral ulcers are the most prevalent oral mucosal diseases globally, and no specific treatment schemes are currently available due to the complexity of oral ulcer diseases. Sleep deprivation increases the risk of a deterioration in oral health. Kouyanqing Granule (KYQG) has been used for decades in Ch...

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Bibliographic Details
Main Authors: Pan Chen, Hongliang Yao, Weiwei Su, Yuying Zheng, Weiyang Fan, Liping Zhang, Tingting Chen, Shuling Wu, Weijian Zhang, Yan He, Zenghao Yan, Yonggang Wang, Peibo Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Pharmacology
Subjects:
oral ulcers
Kouyanqing Granule
sleep deprivation
neuro-immuno-endocrine system
oxidative stress
tryptophan metabolism
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00824/full

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https://www.frontiersin.org/article/10.3389/fphar.2020.00824/full

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