Schwann cell remyelination of the central nervous system: why does it happen and what are the benefits?

Myelin sheaths, by supporting axonal integrity and allowing rapid saltatory impulse conduction, are of fundamental importance for neuronal function. In response to demyelinating injuries in the central nervous system (CNS), oligodendrocyte progenitor cells (OPCs) migrate to the lesion area, prolifer...

Full description

Bibliographic Details
Main Authors: Civia Z. Chen, Björn Neumann, Sarah Förster, Robin J. M. Franklin
Format: Article
Language:English
Published: The Royal Society 2021-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.200352