Bedshift: perturbation of genomic interval sets

Abstract Functional genomics experiments, like ChIP-Seq or ATAC-Seq, produce results that are summarized as a region set. There is no way to objectively evaluate the effectiveness of region set similarity metrics. We present Bedshift, a tool for perturbing BED files by randomly shifting, adding, and...

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Bibliographic Details
Main Authors: Aaron Gu, Hyun Jae Cho, Nathan C. Sheffield
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-021-02440-w