Selection of DNA aptamers against glioblastoma cells with high affinity and specificity.

BACKGROUND: Glioblastoma is the most common and most lethal form of brain tumor in human. Unfortunately, there is still no effective therapy to this fatal disease and the median survival is generally less than one year from the time of diagnosis. Discovery of ligands that can bind specifically to th...

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Bibliographic Details
Main Authors: Dezhi Kang, Jiangjie Wang, Weiyun Zhang, Yanling Song, Xilan Li, Yuan Zou, Mingtao Zhu, Zhi Zhu, Fuyong Chen, Chaoyong James Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3462804?pdf=render