G308A polymorphism of TNF-alpha gene is associated with insulin resistance and histological changes in non alcoholic fatty liver disease patients

Some studies have pointed to a role of TNF-alpha in pathogenesis of non alcoholic fatty liver disease (NAFLD). The aim of our study was to investigate the influence of G308A polymorphism TNF alpha gene on the histological changes, insulin resistance and TNF-alpha levels in overweight patients. A pop...

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Bibliographic Details
Main Authors: Rocio Alter, Daniel Antonio de Luis, Olatz Izaola, Manuel González Sagrado, Rosa Conde, Tomas Alvarez Gago, David Pacheco, Jose Manuel González, María Concepcion Velasco
Format: Article
Language:English
Published: Elsevier 2010-10-01
Series:Annals of Hepatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119316205