AIM2 Stimulation Impairs Reendothelialization and Promotes the Development of Atherosclerosis in Mice

AIM2 Stimulation Impairs Reendothelialization and Promotes the Development of Atherosclerosis in Mice

Background: Atherosclerosis has been shown to result from chronic inflammation caused by constitutive activation of the pattern recognition receptors (PRR), which are principle effectors of the innate immune system. PRR are present in the endosome or on the cellular membrane and can sense the aberra...

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Bibliographic Details
Main Authors: Enzo Lüsebrink, Philip Roger Goody, Catharina Lahrmann, Anna Flender, Sven Thomas Niepmann, Andreas Zietzer, Christian Schulz, Steffen Massberg, Felix Jansen, Georg Nickenig, Sebastian Zimmer, Alexander Otto Krogmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Innate immune system
AIM2
atherosclerosis
immune system
mice
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2020.582482/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2020.582482/full

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