Development of enteric coated sustained release minitablets containing mesalamine

The aim of this study was to develop and evaluate a multiparticulate modified release system, composed of minitablets with a sustained release matrix system coated with a pH-dependent release polymer, using mesalamine as a model drug. Polyox® WSR 1105 was the polymer used in the matrix system and Eu...

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Bibliographic Details
Main Authors: Dayse Fernanda de Souza, Karin Goebel, Itamar Francisco Andreazza
Format: Article
Language:English
Published: Universidade de São Paulo 2013-09-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000300014&lng=en&tlng=en