Thrombin Maybe Plays an Important Role in MK Differentiation into Platelets

Objectives. After development and differentiation, megakaryocytes (MKs) can produce platelets. As is well known, thrombopoietin (TPO) can induce MKs to differentiate. The effect of thrombin on MKs differentiation is not clear. In this study, we used a human megakaryoblastic leukemia cell line (Meg-0...

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Bibliographic Details
Main Authors: Xiao-Lei Yang, Meng-Kai Ge, De-Kui Mao, Ying-Tao Lv, Shu-Yan Sun, Ai-Ping Yu
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2016/9313269