Block by Phytoestrogens of Recombinant Human Neuronal Nicotinic Receptors

ABSTRACT: The effects of phytoestrogens on neuronal nicotinic acetylcholine receptor/channels were examined by expressing recombinant channels in Xenopus oocytes. When functional channels were expressed with human α4 and β2 subuints, daidzein (10 and 100 μM) partially inhibited the ionic current act...

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Bibliographic Details
Main Authors: Ken Nakazawa, Yasuo Ohno
Format: Article
Language:English
Published: Elsevier 2003-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319326234