Current evidence and the emerging role of eltrombopag in severe aplastic anemia
Acquired aplastic anemia (AA) is characterized by a reduced stem cell reserve. Several preclinical studies have confirmed the beneficial effect of thrombopoietin (TPO) on the expansion and maintenance of hematopoietic stem cells (HSCs). Thus, TPO receptor agonists seem to be an ideal therapeutic age...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2021-03-01
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Series: | Therapeutic Advances in Hematology |
Online Access: | https://doi.org/10.1177/2040620721998126 |