Overcoming the growth–infectivity trade‐off in a bacteriophage slows bacterial resistance evolution

Abstract The use of lytic bacteriophages for treating harmful bacteria (phage therapy) is faced with the challenge of bacterial resistance evolution. Phage strains with certain traits, for example, rapid growth and relatively broad infectivity ranges, may enjoy an advantage in slowing bacterial resi...

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Bibliographic Details
Main Authors: Quan‐Guo Zhang, Xiao‐Lin Chu, Angus Buckling
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Evolutionary Applications
Subjects:
Online Access:https://doi.org/10.1111/eva.13260