YKL-40/c-Met expression in rectal cancer biopsies predicts tumor regression following neoadjuvant chemoradiotherapy: a multi-institutional study.

BACKGROUND:Neoadjuvant chemo-radiotherapy (CRT) followed by surgical resection is the standard treatment for locally advanced rectal cancer, although complete tumor pathological regression is achieved in only up to 30% of cases. A clinicopathological and molecular predictive stratification of patien...

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Bibliographic Details
Main Authors: Rebecca Senetta, Eleonora Duregon, Cristina Sonetto, Rossella Spadi, Massimiliano Mistrangelo, Patrizia Racca, Luigi Chiusa, Fernando H Munoz, Umberto Ricardi, Alberto Arezzo, Adele Cassenti, Isabella Castellano, Mauro Papotti, Mario Morino, Mauro Risio, Paola Cassoni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4398550?pdf=render