Cardiac toxicity of coxibs: mechanisms of development and their prevention

Development of highly selective COX-2 inhibitors – coxibs has proved a decreased risk of gastrointestinal toxicity, which was typical for non-selective NSAIDS, according to the evidence-based medicine. But such situation caused an imbalance in the impact on the synthesis of arachidonic acid metaboli...

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Bibliographic Details
Main Authors: O O Yakovleva, A O Zhamba, I O Doroshkevych, T K Vitruk
Format: Article
Language:English
Published: Interdisciplinary Academy of Pain Medicine 2018-11-01
Series:Медицина болю
Subjects:
Online Access:https://painmedicine.org.ua/index.php/pnmdcn/article/view/154