Role of the ESCRT Complexes in Telomere Biology

Eukaryotic chromosomal ends are protected by telomeres from fusion, degradation, and unwanted double-strand break repair events. Therefore, telomeres preserve genome stability and integrity. Telomere length can be maintained by telomerase, which is expressed in most human primary tumors but is not e...

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Bibliographic Details
Main Authors: Anna K. Dieckmann, Vera Babin, Yaniv Harari, Roland Eils, Rainer Konig, Brian Luke, Martin Kupiec
Format: Article
Language:English
Published: American Society for Microbiology 2016-11-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/6/e01793-16