Role of the ESCRT Complexes in Telomere Biology
Eukaryotic chromosomal ends are protected by telomeres from fusion, degradation, and unwanted double-strand break repair events. Therefore, telomeres preserve genome stability and integrity. Telomere length can be maintained by telomerase, which is expressed in most human primary tumors but is not e...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2016-11-01
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Series: | mBio |
Online Access: | http://mbio.asm.org/cgi/content/full/7/6/e01793-16 |