Facilitates Chromatin Transcription Complex Is an “Accelerator” of Tumor Transformation and Potential Marker and Target of Aggressive Cancers

The facilitates chromatin transcription (FACT) complex is involved in chromatin remodeling during transcription, replication, and DNA repair. FACT was previously considered to be ubiquitously expressed and not associated with any disease. However, we discovered that FACT is the target of a class of...

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Bibliographic Details
Main Authors: Henry Garcia, Jeffrey C. Miecznikowski, Alfiya Safina, Mairead Commane, Anja Ruusulehto, Sami Kilpinen, Robert W. Leach, Kristopher Attwood, Yan Li, Seamus Degan, Angela R. Omilian, Olga Guryanova, Olympia Papantonopoulou, Jianmin Wang, Michael Buck, Song Liu, Carl Morrison, Katerina V. Gurova
Format: Article
Language:English
Published: Elsevier 2013-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471300291X