Impact of Aging on the Frequency, Phenotype, and Function of CD161-Expressing T Cells

Immune-aging is associated with perturbed immune responses in the elderly. CD161-expressing T cells, i.e., the previously described subsets of CD161+ CD4+ T cells, CD161high CD8+ T cells, and CD161int CD8+ T cells, are highly functional, pro-inflammatory T cells. These CD161-expressing T cells are c...

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Bibliographic Details
Main Authors: Kornelis S. M. van der Geest, Bart-Jan Kroesen, Gerda Horst, Wayel H. Abdulahad, Elisabeth Brouwer, Annemieke M. H. Boots
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00752/full