Antigen-Antibody Affinity for Dry Eye Biomarkers by Label Free Biosensing. Comparison with the ELISA Technique

Antigen-Antibody Affinity for Dry Eye Biomarkers by Label Free Biosensing. Comparison with the ELISA Technique

The specificity and affinity of antibody-antigen interactions is a fundamental way to achieve reliable biosensing responses. Different proteins involved with dry eye dysfunction: ANXA1, ANXA11, CST4, PRDX5, PLAA and S100A6; were validated as biomarkers. In this work several antibodies were tested fo...

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Bibliographic Details
Main Authors: Maríafe Laguna, Miguel Holgado, Ana L. Hernandez, Beatriz Santamaría, Alvaro Lavín, Javier Soria, Tatiana Suarez, Carlota Bardina, Mónica Jara, Francisco J. Sanza, Rafael Casquel
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:Sensors
Subjects:
photonic sensing cells BICELLs
biosensors
label-free immunoassay
dry eye biomarkers
Online Access:http://www.mdpi.com/1424-8220/15/8/19819

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http://www.mdpi.com/1424-8220/15/8/19819

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