The reno-protective effect of metformin against type 2 diabetic rats via up-regulating renal tissue pigment epithelium-derived factor expression

The reno-protective effect of metformin against type 2 diabetic rats via up-regulating renal tissue pigment epithelium-derived factor expression

Background. Diabetic nephropathy has become the primary cause of end-stage renal disease worldwide. Pigment epithelium-derived factor (PEDF) is an endogenous anti-inflammatory factor in vivo, which can inhibit the expression of pathogenic factors — transforming growth factor β1 and connective tissue...

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Bibliographic Details
Main Authors:	Liu Jiarui, Bi Shuangjie, Ye Shandong
Format:	Article
Language:	English
Published:	Publishing House Zaslavsky 2019-11-01
Series:	Mìžnarodnij Endokrinologìčnij Žurnal
Subjects:	type 2 diabetes mellitus diabetic kidney disease metformin pigment epithelium-derived factor glibenclamide
Online Access:	http://iej.zaslavsky.com.ua/article/view/191680

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