The reno-protective effect of metformin against type 2 diabetic rats via up-regulating renal tissue pigment epithelium-derived factor expression
Background. Diabetic nephropathy has become the primary cause of end-stage renal disease worldwide. Pigment epithelium-derived factor (PEDF) is an endogenous anti-inflammatory factor in vivo, which can inhibit the expression of pathogenic factors — transforming growth factor β1 and connective tissue...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Publishing House Zaslavsky
2019-11-01
|
| Series: | Mìžnarodnij Endokrinologìčnij Žurnal |
| Subjects: | |
| Online Access: | http://iej.zaslavsky.com.ua/article/view/191680 |