Proteinase-Activated Receptor 1 (PAR1) regulates leukemic stem cell functions.

Proteinase-Activated Receptor 1 (PAR1) regulates leukemic stem cell functions.

External signals that are mediated by specific receptors determine stem cell fate. The thrombin receptor PAR1 plays an important role in haemostasis, thrombosis and vascular biology, but also in tumor biology and angiogenesis. Its expression and function in hematopoietic stem cells is largely unknow...

Full description

Bibliographic Details
Main Authors: Nicole Bäumer, Annika Krause, Gabriele Köhler, Stephanie Lettermann, Georg Evers, Antje Hascher, Sebastian Bäumer, Wolfgang E Berdel, Carsten Müller-Tidow, Lara Tickenbrock
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3989293?pdf=render

Internet

http://europepmc.org/articles/PMC3989293?pdf=render

Similar Items