Complement Activation in Autoimmune Bullous Dermatoses: A Comprehensive Review

Complement Activation in Autoimmune Bullous Dermatoses: A Comprehensive Review

Autoimmune bullous dermatoses (AIBD) are characterized by circulating autoantibodies that are either directed against epidermal antigens or deposited as immune complexes in the basement membrane zone (BMZ). The complement system (CS) can be activated by autoantibodies, thereby triggering activation...

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Bibliographic Details
Main Authors: Gareth Edwards, Gilles F. H. Diercks, Marc A. J. Seelen, Barbara Horvath, Martijn B. A. van Doorn, Jeffrey Damman
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
complement
auto-immune bullous dermatosis
bullous pemphigod
epidermolysis bullosa acquisita
mucus membrane pemphigoid
pemphigus
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01477/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01477/full

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