TRAF4 acts as a fate checkpoint to regulate the adipogenic differentiation of MSCs by activating PKM2

TRAF4 acts as a fate checkpoint to regulate the adipogenic differentiation of MSCs by activating PKM2

Background: Mesenchymal stem cells (MSCs) selectively differentiate into adipocytes or osteoblasts, and several molecules control the fate determination of MSCs. Understanding these key checkpoints greatly contributes to the ability to induce specific MSC differentiation for clinical applications. I...

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Bibliographic Details
Main Authors: Shuizhong Cen, Jinteng Li, Zhaopeng Cai, Yiqian Pan, Zehang Sun, Zhaofeng Li, Guiwen Ye, Guan Zheng, Ming Li, Wenjie Liu, Wenhui Yu, Shan Wang, Zhongyu Xie, Peng Wang, Huiyong Shen
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420300979

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http://www.sciencedirect.com/science/article/pii/S2352396420300979

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