Immunological effects of nivolumab immunotherapy in patients with oral cavity squamous cell carcinoma

Immunological effects of nivolumab immunotherapy in patients with oral cavity squamous cell carcinoma

Abstract Background Although checkpoint blockades have become widely used, the immunological impact in cancer patients, especially those with oral cavity squamous cell carcinoma (OCSCC), has not been well studied. Methods The present study assessed the immunological impact of anti-PD-1 (nivolumab) t...

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Bibliographic Details
Main Authors: Ying Xiong, David M. Neskey, Joshua D. Horton, Chrystal M. Paulos, Hannah M. Knochelmann, Kent E. Armeson, M. Rita I. Young
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Cancer
Subjects:
Anti-PD-1 antibody
CD4
CD8
Granzyme B
Immune
Interferon-γ
Online Access:http://link.springer.com/article/10.1186/s12885-020-06726-3

Internet

http://link.springer.com/article/10.1186/s12885-020-06726-3

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