TMEM120A is a coenzyme A-binding membrane protein with structural similarities to ELOVL fatty acid elongase
TMEM120A, also named as TACAN, is a novel membrane protein highly conserved in vertebrates and was recently proposed to be a mechanosensitive channel involved in sensing mechanical pain. Here we present the single-particle cryogenic electron microscopy (cryo-EM) structure of human TMEM120A, which fo...
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-08-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/71220 |