Daily oral supplementation of Hochu-Ekki-To prevents osteoclastic activation and bone loss in ovariectomized mice

Daily oral supplementation of Hochu-Ekki-To prevents osteoclastic activation and bone loss in ovariectomized mice

Bone remodeling is sophisticatedly regulated by two different cell types: bone-resorbing osteoclasts and bone-forming osteoblasts. Hochu-Ekki-To, a Japanese traditional herbal medicine, is commonly used for the treatment of chronic diseases or frailty after an illness; however, its effects on metabo...

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Bibliographic Details
Main Authors: Shinsuke Ochiai, Kazuya Tokumura, Gyujin Park, Kakeru Ozaki, Tetsuhiro Horie, Takanori Yamada, Sayuki Iwahashi, Kaname Ohta, Hiroki Fusawa, Yasuka Okayama, Katsuyuki Kaneda, Takashi Iezaki, Eiichi Hinoi
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Journal of Pharmacological Sciences
Subjects:
Osteoporosis
Osteoclast
Traditional herbal medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861320300979

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http://www.sciencedirect.com/science/article/pii/S1347861320300979

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