Immunohistochemical BRAF V600E Expression and Intratumor BRAF V600E Heterogeneity in Acral Melanoma: Implication in Melanoma-Specific Survival

Immunohistochemical BRAF V600E Expression and Intratumor BRAF V600E Heterogeneity in Acral Melanoma: Implication in Melanoma-Specific Survival

Acral melanoma, a distinct form of cutaneous melanoma originating in the glabrous skin of the palms, soles, and nail beds, has a different genetic background from other subtypes of cutaneous melanoma. The roles of oncogenic <i>BRAF</i> mutations of acral melanoma in pathogenesis and pati...

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Bibliographic Details
Main Authors: Takamichi Ito, Yumiko Kaku-Ito, Maho Murata, Kazuhisa Furue, Che-Hung Shen, Yoshinao Oda, Masutaka Furue
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Journal of Clinical Medicine
Subjects:
acral melanoma
braf
heterogeneity
immunohistochemistry
mutation
prognosis
outcome
survival
acral lentiginous melanoma
ve1
Online Access:https://www.mdpi.com/2077-0383/9/3/690

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https://www.mdpi.com/2077-0383/9/3/690

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