The Link between Purine Metabolism and Production of Antibiotics in <i>Streptomyces</i>

Stress and starvation causes bacterial cells to activate the stringent response. This results in down-regulation of energy-requiring processes related to growth, as well as an upregulation of genes associated with survival and stress responses. Guanosine tetra- and pentaphosphates (collectively refe...

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Bibliographic Details
Main Authors: Smitha Sivapragasam, Anne Grove
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/8/2/76