Exosomes Derived From CircAkap7-Modified Adipose-Derived Mesenchymal Stem Cells Protect Against Cerebral Ischemic Injury

Exosomes Derived From CircAkap7-Modified Adipose-Derived Mesenchymal Stem Cells Protect Against Cerebral Ischemic Injury

BackgroundCerebral ischemic injury is a complicated pathological process. Adipose-derived stromal cells (ADSCs) have been used as a therapeutic strategy, with their therapeutic effects chiefly attributed to paracrine action rather than trans-differentiation. Studies have shown that circAkap7 was fou...

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Bibliographic Details
Main Authors: Limin Xu, Haifeng Ji, Yufeng Jiang, Liying Cai, Xiaoyin Lai, Feifei Wu, Rongguo Hu, Xuelian Yang, Huan Bao, Mei Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
cerebral ischemic injury
exosomes
circular RNA
autophagy
oxidative stress
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.569977/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.569977/full

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