Sequential chromatin immunoprecipitation to detect SUMOylated MeCP2 in neurons

The small ubiquitin-like modifier (SUMO) is a short peptide that can be covalently linked to proteins altering their function. SUMOylation is an essential post-translational modification (PTM). Because of its dynamic nature, low abundance levels, and technical limitations, the occupation of endogeno...

Full description

Bibliographic Details
Main Authors: Tao Wu, Mary E. Donohoe
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Biochemistry and Biophysics Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580816300036