Sequential chromatin immunoprecipitation to detect SUMOylated MeCP2 in neurons
The small ubiquitin-like modifier (SUMO) is a short peptide that can be covalently linked to proteins altering their function. SUMOylation is an essential post-translational modification (PTM). Because of its dynamic nature, low abundance levels, and technical limitations, the occupation of endogeno...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-03-01
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Series: | Biochemistry and Biophysics Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405580816300036 |