Rhodopsin optogenetic toolbox v2.0 for light-sensitive excitation and inhibition in Caenorhabditis elegans.

In optogenetics, rhodopsins were established as light-driven tools to manipulate neuronal activity. However, during long-term photostimulation using channelrhodopsin (ChR), desensitization can reduce effects. Furthermore, requirement for continuous presence of the chromophore all-trans retinal (ATR)...

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Bibliographic Details
Main Authors: Amelie Bergs, Christian Schultheis, Elisabeth Fischer, Satoshi P Tsunoda, Karen Erbguth, Steven J Husson, Elena Govorunova, John L Spudich, Georg Nagel, Alexander Gottschalk, Jana F Liewald
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5794093?pdf=render