In vitro and in vivo evaluation of liposomes modified with polypeptides and red cell membrane as a novel drug delivery system for myocardium targeting

Ischemic cardiac disease (ICD) is a cardiovascular disease with high morbidity and mortality. In this study, a novel myocardial targeted drug delivery system was developed represented by co-modified liposomes consisting of red cell membrane (RCM), and the peptides TAT and PCM. Liposomes were prepare...

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Bibliographic Details
Main Authors: Xueyan Liu, Liangke Zhang, Wengao Jiang, Zhangyou Yang, Zongjie Gan, Chao Yu, Ran Tao, Huali Chen
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Drug Delivery
Subjects:
tat
pcm
Online Access:http://dx.doi.org/10.1080/10717544.2020.1754525