The Apolipoprotein E Antagonistic Pleiotropy Hypothesis: Review and Recommendations
Research on apolipoprotein E (APOE) has consistently revealed a relationship between the gene's ε4 allele and risk for development of Alzheimer's disease (AD). However, research with younger populations of ε4 carriers has suggested that the APOE ε4 allele may in fact be beneficial in earli...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2011-01-01
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Series: | International Journal of Alzheimer's Disease |
Online Access: | http://dx.doi.org/10.4061/2011/726197 |