Increased production of ganoderic acids by overexpression of homologous farnesyl diphosphate synthase and kinetic modeling of ganoderic acid production in Ganoderma lucidum

Increased production of ganoderic acids by overexpression of homologous farnesyl diphosphate synthase and kinetic modeling of ganoderic acid production in Ganoderma lucidum

Abstract Background Ganoderic acids (GAs), derived from the medicinal mushroom Ganoderma lucidum, possess anticancer and other important pharmacological activities. To improve production of GAs, a homologous farnesyl diphosphate synthase (FPS) gene was overexpressed in G. lucidum. Moreover, the infl...

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Bibliographic Details
Main Authors: Yu Fei, Na Li, De-Huai Zhang, Jun-Wei Xu
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Microbial Cell Factories
Subjects:
Ganoderma lucidum
Ganoderic acid
Farnesyl diphosphate synthase
Genetic engineering
Modeling
Production kinetics
Online Access:http://link.springer.com/article/10.1186/s12934-019-1164-3

Internet

http://link.springer.com/article/10.1186/s12934-019-1164-3

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