A detection and quantification label-free tool to speed up downstream processing of model mucins.

Mucins are high-molecular weight glycoproteins (0.25-20 MDa) containing one or more domains that are heavily O-glycosylated. Their implications as targets for cancer treatment have increased the interest in these glycoproteins, mainly in the fields of vaccines and antibodies. However, mucins present...

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Bibliographic Details
Main Authors: Sofia B Carvalho, Ana Sofia Moreira, Joana Gomes, Manuel J T Carrondo, David J Thornton, Paula M Alves, Julia Costa, Cristina Peixoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5760085?pdf=render