Whole‐exome sequencing and genome‐wide association studies identify novel sarcopenia risk genes in Han Chinese

Whole‐exome sequencing and genome‐wide association studies identify novel sarcopenia risk genes in Han Chinese

Abstract Sarcopenia is a complex polygenic disease, and its molecular mechanism is still unclear. Whole lean body mass (WLBM) is a heritable trait predicting sarcopenia. To identify genomic loci underlying, we performed a whole‐exome sequencing (WES) of WLBM variation with high sequencing depth (mor...

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Bibliographic Details
Main Authors: Shu Ran, Xiao He, Zi‐Xuan Jiang, Yu Liu, Yu‐Xue Zhang, Lei Zhang, Gui‐Shan Gu, Yufang Pei, Bao‐Lin Liu, Qing Tian, Yong‐Hong Zhang, Jing‐Yu Wang, Hong‐Wen Deng
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
Sarcopenia
single‐nucleotide polymorphism (SNP)
whole lean body mass (WLBM)
whole‐exome sequencing (WES)
Online Access:https://doi.org/10.1002/mgg3.1267

Internet

https://doi.org/10.1002/mgg3.1267

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