Novel phthalimide based analogues: design, synthesis, biological evaluation, and molecular docking studies

Pyrazolylphthalimide derivative 4 was synthesized and reacted with different reagents to afford the target compounds imidazopyrazoles 5-7, pyrazolopyrimidines 9, 12, 14 and pyrazolotriazines 16, 17 containing phthalimide moiety. The prepared compounds were established by different spectral data and...

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Bibliographic Details
Main Authors: Ismail M. M. Othman, Mohamed A. M. Gad-Elkareem, Mohamed El-Naggar, Eman S. Nossier, Abd El-Galil E. Amr
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
Online Access:http://dx.doi.org/10.1080/14756366.2019.1637861