Probing cellular mechanoadaptation using cell-substrate de-adhesion dynamics: experiments and model.

Physical properties of the extracellular matrix (ECM) are known to regulate cellular processes ranging from spreading to differentiation, with alterations in cell phenotype closely associated with changes in physical properties of cells themselves. When plated on substrates of varying stiffness, fib...

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Bibliographic Details
Main Authors: Soumya S S, Lakshmi Kavitha Sthanam, Ranjith Padinhateeri, Mandar M Inamdar, Shamik Sen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4157833?pdf=render