The inhibitory effect of the hepatitis B virus singly-spliced RNA-encoded p21.5 protein on HBV nucleocapsid formation.

Hepatitis B virus (HBV) is the smallest DNA virus and the major cause of acute and chronic hepatitis. The 3.2 kb HBV viral genome generates four major species of unspliced viral transcript as well as several alternatively spliced RNAs. A 2.2 kb singly-spliced RNA is the most abundant spliced RNA and...

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Main Authors: Yi-Ling Wang, Gan-Guang Liou, Chao-Hsiung Lin, Mong-Liang Chen, Tzer-Min Kuo, Kuen-Nan Tsai, Chien-Choao Huang, Ya-Ling Chen, Li-Rung Huang, Yu-Chi Chou, Chungming Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4364729?pdf=render