Association between Leptin, Metabolic Factors and Liver Histology in Patients with Chronic Hepatitis C

BACKGROUND: Steatosis is common in hepatitis C virus (HCV)-infected patients and likely accelerates fibrosis progression. Leptin, the peptide product of the obesity gene (ob), has been implicated in hepatic fibrogenesis; circulating levels of leptin correlate with body fat mass. The objective of the...

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Bibliographic Details
Main Authors: Robert P Myers, Djamila Messous, Thierry Poynard, Francoise Imbert-Bismut
Format: Article
Language:English
Published: Hindawi Limited 2007-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2007/876076