High Frequency Hearing Loss and Hyperactivity in DUX4 Transgenic Mice.

High Frequency Hearing Loss and Hyperactivity in DUX4 Transgenic Mice.

Facioscapulohumeral muscular dystrophy (FSHD) is caused by mutations leading to ectopic expression of the transcription factor DUX4, and encompasses both muscle-related and non-muscle phenotypes. Mouse models bearing this gene represent valuable tools to investigate which pathologies are due to DUX4...

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Bibliographic Details
Main Authors: Abhijit Dandapat, Benjamin J Perrin, Christine Cabelka, Maria Razzoli, James M Ervasti, Alessandro Bartolomucci, Dawn A Lowe, Michael Kyba
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4792399?pdf=render

Internet

http://europepmc.org/articles/PMC4792399?pdf=render

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