Regulation of Pancreatic β Cell Mass by Cross-Interaction between CCAAT Enhancer Binding Protein β Induced by Endoplasmic Reticulum Stress and AMP-Activated Protein Kinase Activity.

Regulation of Pancreatic β Cell Mass by Cross-Interaction between CCAAT Enhancer Binding Protein β Induced by Endoplasmic Reticulum Stress and AMP-Activated Protein Kinase Activity.

During the development of type 2 diabetes, endoplasmic reticulum (ER) stress leads to not only insulin resistance but also to pancreatic beta cell failure. Conversely, cell function under various stressed conditions can be restored by reducing ER stress by activating AMP-activated protein kinase (AM...

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Bibliographic Details
Main Authors: Tomokazu Matsuda, Hiroaki Takahashi, Yusuke Mieda, Shinobu Shimizu, Takeshi Kawamoto, Yuki Matsuura, Tomoko Takai, Emi Suzuki, Ayumi Kanno, Maki Koyanagi-Kimura, Shun-ichiro Asahara, Alberto Bartolome, Norihide Yokoi, Hiroshi Inoue, Wataru Ogawa, Susumu Seino, Yoshiaki Kido
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4474801?pdf=render

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http://europepmc.org/articles/PMC4474801?pdf=render

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