Cyclin-Dependent Kinase Inhibitors as Marketed Anticancer Drugs: Where Are We Now? A Short Survey

In the early 2000s, the anticancer drug imatinib (Glivec®) appeared on the market, exhibiting a new mode of action by selective kinase inhibition. Consequently, kinases became a validated therapeutic target, paving the way for further developments. Although these kinases have been thoroughly studied...

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Bibliographic Details
Main Authors: Gaëlle Mariaule, Philippe Belmont
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:Molecules
Subjects:
CDK
Online Access:http://www.mdpi.com/1420-3049/19/9/14366